Search on: INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS 
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Descriptor English:   Insulin-Like Growth Factor Binding Proteins 
Descriptor Spanish:   Proteínas de Unión a Factor de Crecimiento Similar a la Insulina 
Descriptor Portuguese:   Proteínas de Ligação a Fator de Crescimento Insulin-Like 
Synonyms English:   IGF-Binding Proteins
IGFBP
Somatomedin-Binding Proteins  
Tree Number:   D12.776.157.420
Definition English:   A family of soluble proteins that bind insulin-like growth factors and modulate their biological actions at the cellular level. (Int J Gynaecol Obstet 1992;39(1):3-9) 
Indexing Annotation English:   GEN or unspecified; prefer specifics; /biosyn /drug eff /physiol /ultrastruct permitted; DF: note short X refs
History Note English:   2005(1996) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   32714 
Unique Identifier:   D018969 

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